gabapentin drug interactions

Its unknown if gabapentin can harm your unborn baby. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Elan Pharmaceuticals Sorry, we have no data available. Some of the mostcommon side effects of gabapentininclude drowsiness, weakness, dizziness, headache, and stomach upset. Tegretol (carbamazepine)." Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Greenwich Biosciences LLC Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid that was first approved for use in the United States in 1993. Medically Reviewed By Kathleen Oroho Linskey, PharmD. Curr Top Med Chem. Until more data becomes available, the developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for this drug and any potential adverse effects on the breastfed infant from this drug or from the underlying maternal condition. As noted before, gabapentin and benzodiazepines are both classified as CNS depressants, and thecombination can cause an intense sedative effect. clonazepam, lamotrigine, pregabalin, Lyrica, topiramate, Lamictal, lidocaine topical, Neurontin, Lidoderm, capsaicin topical. These include opioids, benzodiazepines, and alcohol. Learn what side effects to watch for, drugs to avoid while taking gabapentin, how to take gabapentin and other important questions and answers. Maintenance: Subsequently titrate as needed up to 600 mg orally every 8 hours; doses greater than 1800 mg/day have demonstrated no additional benefit. If you take gabapentin and benzodiazepines, it is very important to avoid taking other products that can further intensify drowsiness or dizziness, such asalcohol. Ages 3-12 years: Risk of neuropsychiatric adverse events, including emotional lability, hostility, thought disorders, and hyperkinesia. Omni Laboratories Division, Warner Lambert Canada Inc. Dipentocaine Topical Cream Compounding Kit. Take gabapentin by mouth as directed by your doctor, usually once a day with the evening meal. 2005 - 2023 WebMD LLC. It should not be used in place of the advice of your physician or other qualified healthcare providers. Vestal C. The Pew Charitable Trusts. (1986): 830-9. Selected from data included with permission and copyrighted by First Databank, Inc. Creatinine clearance greater than 60 mL/min: 300-1200 mg orally twice daily, Creatinine clearance 30-60 mL/min: 200-700 mg every 12 hours, Creatinine clearance 15-29 mL/min: 200-700 mg once per day, Creatinine clearance less than 15 mL/min: 100-300 mg once per day, Administer supplemental dose (range 125-350 mg) post, Creatinine clearance is greater than or equal to 60 mL/min: 1800 mg daily with evening meal, Creatinine clearance 30-59 mL/min: 600-1800 mg daily with evening meal, Creatinine clearance greater than 30 mL/min or hemodialysis: Do not administer, burning or prickling sensation in hands or feet, skin reaction caused by acute hypersensitivity. (2013). Taking gabapentin andValium(diazepam), a benzodiazepine may be necessary for managing seizure disorders in certain patients. Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum. American Society of Health-System Pharmacists. Gabapentin is removed by hemodialysis and should be administered after dialysis. The risk or severity of adverse effects can be increased when Gabapentin is combined with Alimemazine. Depomed Inc The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Avoid combinations; the risk of the interaction outweighs the benefit. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. What Are Side Effects Associated with Using Common Eliquis and Gabapentin interactions: Abdominal cramps: 70 reports Abdominal distension: 22 reports Abdominal pain: 70 reports Abdominal pain upper: 54 reports Abnormal heart rhythms: 39 reports Acupuncture and pain: 21 reports Acute kidney failure: 200 reports Acute mi (heart attack): 44 reports Alternative medicine - pain relief: 21 reports 2015 Dec;20(4):403-9. doi: 10.1111/jns.12149. You should avoid or limit the use of alcohol while being treated with gabapentin. Clin Pharmacokinet. Neurontin (gabapentin) Product Label. May 1, 2013. Take Gralise tablets with your evening meal. Biocodex USA Anesth Analg. (2001): Cerner Multum, Inc. "UK Summary of Product Characteristics." Gabapentin is a common prescription, and it is often used in combination with other medications. Gabapentin belongs to a class of drugs known as anti-seizure drugs. Dilantin (phenytoin)." Always take gabapentin exactly as prescribed. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. Its available as 100-, 300- or 400-milligram gelatin capsules (Neurontin or generic gabapentin). There are 266 drug interactions with gabapentin. Avoid life-threatening adverse drug events & improve clinical decision support. restless legs syndrome, an extreme discomfort in the calf muscles when sitting or lying down, additional medication to treat partial seizures, diabetic complication causing injury to some body nerves. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Horizant (gabapentin)." Some medications may be better absorbed if taken with food or may have more favorable blood levels if taken with other medications that affect metabolic enzymes. . Moderate Potential Hazard, High plausibility. This survey is being conducted by the WebMD marketing sciences department. 2005 - 2023 WebMD LLC. Does Gabapentin interact with other medications? In addition, it may be prudent to refrain from dispensing large quantities of medication to such patients. Check with your physician for additional information about side effects. Drug Interaction Classification; These classifications are only a guideline. Addiction-prone individuals, such as those with a history of alcohol or substance abuse, should be under careful surveillance or medical supervision when treated with these agents. While it is generally recommended that this combination is avoided, doctors may feel that the combination is necessary for treatment in certain patients. Curr Opin Pharmacol. Gabapentin 1200 Mg Report any type of new or getting worse signs to your physician, such as: state of mind or habits modifications, stress and anxiety, sadness, or if you feel flustered, unfavorable, agitated, hyper (emotionally or literally) Gabapentin systemic 300 mg (IG322 300 mg). Gabapentin treats seizures by decreasing abnormal . Moderately clinically significant. However, the individuals in these reports experienced symptoms after discontinuing higher-than-recommended doses of gabapentin and for uses for which the drug was not approved. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Things to remember when you fill your prescription. Its available as 300- and 600-milligram tablets (Gralise) and 600- and 800-milligram tablets (Neurontin or generic gabapentin). Adderall (amphetamine / dextroamphetamine), Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, Drug class: gamma-aminobutyric acid analogs. Accessed August 3, 2019. Keep out of reach of children. Drug Metab Pharmacokinet. If you have had a seizure, it means you have epilepsy. Pfizer U.S. Pharmaceuticals Group Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Things to remember when you fill your prescription. Accessed August 4, 2019. Minimally clinically significant. All rights reserved. The dosage is based on your medical condition and response to treatment. Diacomit (stiripentol)." ", See also "What Are Side Effects Associated with Using Gabapentin?". Anxiolytic, sedative, and hypnotic agents have the potential to cause dependence and abuse. Moderate Interactions. Drug created at June 13, 2005 13:24 / Updated at January 18, 2023 12:16. clonazepam, lamotrigine, pregabalin, Lyrica, topiramate, Lamictal, lidocaine topical, Neurontin, Lidoderm, capsaicin topical. Gabapentin may increase the central nervous system depressant (CNS depressant) activities of Aclidinium. Drug interactions can also contribute to the cost of healthcare, as a serious drug interaction could result in injury, hospitalization, or rarely, death. Dose gradually to 1800 mg/day orally; take once a day with evening meal. Risk Summary: There are no data on the developmental risks associated with use of this drug in pregnant women; in animal studies, developmental toxicity was observed at doses estimated to be similar or lower than those used clinically. (2001): "Product Information. Gabapentin has no known severe interactions with any drugs. Highly clinically significant. Sorry, we have no data available. (2001): "Product Information. Epub 2005 Dec 22. This document does not contain all possible interactions. Epub 2013 Apr 6. Do not discontinue abruptly as it may increase seizure frequency; gradually taper over a minimum of 1 week. Do not crush or chew sustained-release tablets. AU TGA pregnancy category: B3US FDA pregnancy category: Not assigned. Potiga (ezogabine)." Disease Interactions Doctors should take special consideration in regards to dosing gabapentin in patients with the following: Renal (kidney) dysfunction and hemodialysis (kidney dialysis) Suicidal tendencies Myasthenia gravis (muscle weakness and fatigue, resulting in droopy facial features) Respiratory disease Seizure disorder Substance abuse O 0, Cerner Multum, Inc. "Australian Product Information." Lyricaand gabapentin are not typically recommended to be taken together because they both mimic the effects of the same chemical in the brain. All rights reserved. Are pregnant, trying to become pregnant or are breastfeeding. Improve clinical decision support with information on. The Recovery Village Drug and Alcohol Rehab There are 4 disease interactions with gabapentin which include: drug dependence renal dysfunction suicidal tendency hemodialysis Report options Share by QR Code Email this report to a friend, doctor, or patient Ask questions, find answers More about gabapentin gabapentin consumer information Check interactions Compare alternatives Pricing & coupons It is created by eHealthMe based on reports of 5,581 people who take Gabapentin and Xarelto from the FDA, and is updated regularly. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT" (2012): "Product Information. Ambien (zolpidem)." [, Sills GJ: The mechanisms of action of gabapentin and pregabalin. "Product Information. Generic Name Gabapentin DrugBank Accession Number DB00996 Background. This is the case for every drug out there, including gabapentin, which is a type of anticonvulsant, or anti-seizure medication. This combination may cause serious life threatening reactions. Swallow the whole or split tablet without crushing or chewing. O 0. Review our medical disclaimer. Antiepileptic drugs (AEDs) have been associated with an increased risk of suicidal thoughts or behavior in patients taking these drugs for any indication. Co-administration with food slightly alters pharmacokinetics, but not to a clinically significant extent. Applicable conditions: Depression, Psychosis. "Product Information. Don't chew, break or crush. If its just a few hours before its time to take your next dose, take only one dose. Gabapentin transfers into breast milk, consult with your physician. 2010 Oct;49(10):661-9. doi: 10.2165/11536200-000000000-00000. The risk or severity of adverse effects can be increased when Alosetron is combined with Gabapentin. Pooled analyses of 199 placebo-controlled clinical studies involving the use of 11 different AEDs across multiple indications in either monotherapy or adjunctive therapy for a median treatment duration of 12 weeks (up to a maximum of 24 weeks) showed that patients receiving AEDs had approximately twice the risk of suicidal thinking or behavior compared to patients receiving placebo. Select a condition to view a list of medication options. Does Lyrica Interact with other Medications? Gabapentin is available in both branded and generic forms. In rats, an increased incidence of hydroureter and/or hydronephrosis have been observed in offspring at all doses, the lowest dose being similar to the maximum recommended human dose on a mg/m2 basis. Gabapentin is used to: Prevent and control partial seizures. The oral solution contains 250 millgrams of gabapentin per 5 milliliter (50 mg per mL) Neurontin or generic gabapentin. You can take the second half for your next dose. Disclaimer: This content should not be considered complete and should not be used in place of a call or visit to a healthcare professional. Brand names of gabapentin include Horizant, Gralise and Neurontin. 8 . Quintero, Gabriel C. Review about gabapentin misuse, interact[]ns, and side effects. Journal of Experimental Pharmacology, February 9, 2017. Call (888) 966-8152 Why call us? The phase IV clinical study analyzes what interactions people who take Gabapentin and Xarelto have. Gabapentin is in a class of medications called anticonvulsants. We comply with the HONcode standard for trustworthy health information. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. 2023 The Recovery Village Drug and Alcohol Rehab All Rights Reserved. Antihistamine-containing cold, cough and allergy products. In patients who have developed tolerance, overdosage can still produce respiratory depression and death. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. (2002): "Product Information. Selected from data included with permission and copyrighted by First Databank, Inc. Build, train, & validate predictive machine-learning models with structured datasets. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. combination can cause an intense sedative effect, Gabapentin Signs, Symptoms, and Side Effects, Review about gabapentin misuse, interact[]ns, and side effects, New Uses for Older Drugs: The Tales of A[]mide, and Gabapentin. Absorption of gabapentin is thought to occur solely via facilitated transport by the LAT1 transporter within the intestines.5 As this process is saturable, the oral bioavailability of gabapentin is inversely proportional to the administered dose - the oral bioavailability of a 900mg/day regimen is approximately 60%, whereas a 4800mg/day regimen results in only 27% bioavailability.16,18 The Tmax of gabapentin has been estimated to be 2-3 hours.17,5 Food has no appreciable effect on gabapentin absorption.16,18, The apparent volume of distribution of gabapentin after IV administration is 586 L.16,17 The drug is found in the CSF in concentrations approximately 9-20% of the corresponding plasma concentrations and is secreted into breast milk in concentrations similar to that seen in plasma.16,17,5, Less than 3% of an orally administered dose of gabapentin is bound to plasma proteins.16,17, Gabapentin is not appreciably metabolized in humans16,17 - in humans, metabolites account for less than 1% of an administered dose, with the remainder being excreted as unchanged parent drug in the urine.5, Gabapentin is eliminated solely in the urine as unchanged drug.16,17 Cimetidine, an inhibitor of renal tubular secretion, reduces clearance by approximately 12%, suggesting that some degree of tubular secretion is involved in the renal elimination of gabapentin.5, The elimination t1/2 of gabapentin in patients with normal renal function is 5-7 hours.16,17,5 In patients with reduced renal function, the elimination t1/2 may be prolonged - in patients with a creatinine clearance of <30 mL/min, the reported half-life of gabapentin was approximately 52 hours.16,17, Both the plasma clearance and renal clearance of gabapentin are directly proportional to the patient's creatinine clearance due to its primarily renal elimination.16,17,5, The oral TDLo of gabapentin in humans is 2.86 mg/kg and the LD50 in rats has been found to be >8000 mg/kg.21 Symptoms of overdose are consistent with the drug's adverse effect profile and involve CNS depression (e.g. Severe Interactions These medications are not usually taken together. 2016 Feb;22(1 Epilepsy):132-56. doi: 10.1212/CON.0000000000000289. Therapy with gabapentin should be administered cautiously in patients with impaired renal function. There are 4 disease interactions with gabapentin which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Some common combinations of gabapentin with other medications include: If you or someone you know is struggling with a substance use disorder orco-occurring mental healthissue, The Recovery Village can help. Semin Cell Dev Biol. 2006 Jan;102(1):182-7. Drug reaction with eosinophilia and systemic symptoms, also known as multi-organ hypersensitivity, reported; some of these events have been fatal or life-threatening; typically presents with fever, rash, and/or lymphadenopathy in association with other organ system involvement (hepatitis, nephritis, hematologic abnormalities, myocarditis, and myositis) and may resemble an acute viral infection. MedlinePlus. This survey is being conducted by the WebMD marketing sciences department. The risk of suicidal thoughts and behavior should be carefully assessed against the risk of untreated illness, bearing in mind that epilepsy and many other conditions for which AEDs are prescribed are themselves associated with morbidity and mortality and an increased risk of suicidal thoughts and behavior. Zogenix, Inc Minimally clinically significant. Parke-Davis These medications may cause some risk when taken together. Drug interactions are reported among people who take Acetaminophen and Gabapentin. Renal impairment is present, gabapentin dose reduction may be required, depending on renal function. Applicable conditions: Drug Abuse/Dependence Anxiolytic, sedative, and hypnotic agents have the potential to cause dependence and abuse. The branded gabapentin enacarbil product Horizant is approved for restless legs syndrome and PHN. Does It Work? Some mixtures of medications can lead to serious and even fatal consequences. Accessed August 3, 2019. Marinus Pharmaceuticals, Inc Medisca Inc There are no controlled data in human pregnancy. This lesson describes some of its interactions with other drugs and . It's not classified as a controlled substance in most states. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. The absence of an interaction does not necessarily mean no interactions exist. If you have any questions about the interaction between gabapentin and an antacid, talk to your doctor or pharmacist. After prolonged use or if dependency is suspected, withdrawal of medication should be undertaken gradually using a dosage-tapering schedule. Eur Neuropsychopharmacol. Day 15 and after (maintenance): 1800 mg orally once a day. These medications may cause some risk when taken together. Please contact your doctor or pharmacist. Administration of live or attenuated live vaccine (Advisory Committee on Immunization Practices (ACIP) and American Academy of Family Physicians (AAFP) state that administration of live virus vaccines usually is not contraindicated in patients receiving corticosteroid therapy as short-term (less than 2 weeks) treatment, in low-to-moderate dosages, as long-term alternate-day treatment with short-acting preparations, or in maintenance of physiologic dosages, such as, replacement therapy. These medications may interact and cause very harmful effects. When taking these antacids, such as Maalox, it is recommended to take gabapentin at least two hours after taking the antacid. A small number of studies have reported misuse and abuse of gabapentin. Never take more than one dose in an attempt to catch up. Individuals experienced double vision, slurred speech, drowsiness, diarrhea and sluggishness. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Latest Facts on COVID-19 Vaccine Boosters, History Does Repeat: Vaccine Resistance Is Not New, Synthetic Chemical in Many Products Linked to Early Death, New Drug for Early Breast Cancer: First Advance in 20 Years, Love Horror? She earned her Doctorate of Pharmacy from Rutgers University. The phase IV clinical study analyzes what interactions people who take Fluoxetine and Gabapentin have. Treatment Locations Insurance About Us Guides Admissions Addiction Treatment Have questions or ready to start treatment? Extended release formulation (Gralise) not interchangeable with immediate release. Uses. . Coming to a Cleveland Clinic location?Cole Eye entrance closingVisitation, mask requirements and COVID-19 information. To provide information regarding the effects of in utero exposure to this drug, pregnant patients should be encouraged to enroll in the North American Antiepileptic Drug (NAAED) Pregnancy Registry. Gabapentin can be used in adults and children age 3 and older who have partial seizures. InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12), Use our structured and evidence-based datasets to. Lyrica is the brand name for the medication pregabalin, and taking gabapentin with Lyrica is considered a duplication of therapy. Fintepla (fenfluramine)." Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Gabapentin is also used to manage a condition called postherpetic neuralgia, which is pain that occurs after shingles. J Biol Chem. (2001): Gericke CA, Ludolph AC "Chronic abuse of zolpidem." Epub 2006 Sep 24. Major Potential Hazard, Moderate plausibility. Serious Interactions of Gabapentin include: Moderate Interactions of Gabapentin include: Gabapentin has mild interactions with at least 21 different drugs. [, Cheng JK, Chen CC, Yang JR, Chiou LC: The antiallodynic action target of intrathecal gabapentin: Ca2+ channels, KATP channels or N-methyl-d-aspartic acid receptors? Toxicology Data Network. The risk or severity of adverse effects can be increased when Almotriptan is combined with Gabapentin. Serious breathing problems can happen if you take gabapentin with drugs that cause severe sleepiness or decreased awareness. [, Patsalos PN, Berry DJ, Bourgeois BF, Cloyd JC, Glauser TA, Johannessen SI, Leppik IE, Tomson T, Perucca E: Antiepileptic drugs--best practice guidelines for therapeutic drug monitoring: a position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic Strategies. See additional information. (Kentucky, West Virginia, Michigan, Tennessee, and Virginia have reclassified gabapentin as a Schedule V controlled substance). GlaxoSmithKline Epidiolex (cannabidiol)." J Peripher Nerv Syst. Like gabapentin,benzodiazepinesare classified as CNS depressants and can intensify the drowsiness and dizziness side effects of gabapentin. An expert panel has deemed this drug is an acceptable choice for refractory restless leg syndrome during lactation. Usually avoid combinations; use it only under special circumstances. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. If you are taking these medications together, talk to your doctor or pharmacist about the combination. Understanding which medications interact with gabapentin and knowing how to take gabapentin safely will help you live a healthier life. Aquachloral Supprettes (chloral hydrate)." [, Martins DF, Prado MR, Daruge-Neto E, Batisti AP, Emer AA, Mazzardo-Martins L, Santos AR, Piovezan AP: Caffeine prevents antihyperalgesic effect of gabapentin in an animal model of CRPS-I: evidence for the involvement of spinal adenosine A1 receptor. Avoiding Opioids, Many Patients in Pain Get Gabapentin Instead. During the first 2 weeks of treatment, your doctor may gradually increase your dose so your body can adjust to the medication. Take Horizant tablets with food. UCB Pharma Inc . Gabapentin is used with other medications to prevent and control seizures. (Wait two hours after taking aluminum and magnesium-containing antacids before taking gabapentin.). Information on the registry can also be found at the website http://www.aedpregnancyregistry.org/. (2016): "Product Information. Gabapentin. (n.d.). Gabapentin systemic 300 mg (IG322 300 mg). If you forget to take a dose of gabapentin, take it as soon as you remember. Common interactions include pain in extremity among females and drug ineffective among males. Gabapentin? Epub 2018 Jul 18. Minimally clinically significant. 16 It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures 14,5 - today it is also widely used to treat neuropathic pain. 2006 Oct;17(5):565-70. Continuum (Minneap Minn). Patient Drug Interactions Source: RxList. Cerebyx (fosphenytoin)." Animal studies have revealed evidence of developmental toxicity (increased fetal skeletal and visceral abnormalities, and increased embryofetal mortality) when administered at doses similar to, or lower than expected clinical doses. (2009): "Product Information. Antiepileptic drugs increase risk of suicidal thoughts or behavior in patients taking these drugs for any indication; monitor for emergence or worsening depression, suicidal thoughts or behavior, and/or any unusual changes in mood or behavior. Parke-Davis Doing so helps to prevent accidental underdose oroverdose of hydrocodone. With maternal doses up to 2.1 g/day, estimated doses for fully breastfed infants are 0.2 to 1.3 mg/kg/day (equivalent to 1.3 to 3.8% of the maternal weight-adjusted dose). The risk or severity of adverse effects can be increased when Acetazolamide is combined with Gabapentin. The bioavailability of Gabapentin can be decreased when combined with Almasilate. Gabapentin is not a narcotic. Check with your physician if you have health questions or concerns. Briviact (brivaracetam)." Gabapentin, also known by its brand name Neurontin, is a medication that has been used in the United States since the early 1990s. These include antihistamines as well as products that contain magnesium or aluminum. Use WebMD's Drug Interaction Checker tool to find and identify potentially harmful and unsafe combinations of prescription medications by entering two or more drugs in question. (1993): 374-5. Klonopin (clonazepam)." Some common combinations of gabapentin and OTC medications for allergy relief and pain relief include: Taking gabapentin and antacids that contain magnesium hydroxide or aluminum hydroxide causes a reduction in the concentration of gabapentin in the body. The phase IV clinical study analyzes what interactions people who take Acetaminophen and Gabapentin have. Vivus Inc Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. There are 266 drugs known to interact with Avoid alcohol. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Also, do not split sustained-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Umatilla, FL 32784. Last reviewed by a Cleveland Clinic medical professional on 07/01/2021. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Qsymia (phentermine-topiramate)." Of the total drug interactions, "Product Information. Parke-Davis Sorry, we have no data available. Comments:-Breastfed infants should be monitored for drowsiness, adequate weight gain, and developmental milestones, especially when used in combination with other anticonvulsant or psychotropic drugs and in younger, exclusively breastfed infants.-Some authorities suggest discontinuing nursing or discontinuing use of this drug while breastfeeding due to the potential for serious adverse reactions in the breastfed infant. [, Maneuf YP, Luo ZD, Lee K: alpha2delta and the mechanism of action of gabapentin in the treatment of pain. Also, never change your dose without talking to your provider first. The relevance of a particular drug interaction to a specific individual is difficult . 1996-2023 RxList, Inc. All rights reserved. Does Gabapentin interact with other medications? The Recovery Village aims to improve the quality of life for people struggling with substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Neurology 44 Gabapentin possesses CNS depressant activity that may be potentiated by co-administration with alcohol. Gabapentin capsules. Carefully measure the liquid formulation of gabapentin using the measuring device that comes with the drug.

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